Novartis Open Source Initiative

N-nitrosamine Autonomous Carcinogenic Potency Categorization Approach Calculation Tool

The package analyzes chromatin and multi-omic experiments. It extends the MultiAssayExperiment object and builds a ChrawExperiment object from ENCODE’s output. It performs QC plotting, identifies differential events and other functionalities. More details in package vignettes.

A bslib toolkit for building modern, themeable dashboards in Shiny.

A Python library for benchmarking uncertainty estimation and quantification methods for Machine Learning models predictions.

Deep survival analysis made easy

Applied modelling in drug development: flexible Bayesian regression modelling in Stan via brms

Exploratory Graphics for PKPD data

Implementation of caMPO (Correlation-aware Multiparameter Optimization), a method for deriving data-driven non-negative MPO weights from property correlation structure in drug discovery.

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This pipeline is designed for AAV integration site analysis using Target Enrichment Sequencing (TES) coupled with PacBio long-read sequencing. It enables the detection of integration site breakpoints and provides information on the structure of the integrated AAV vector genome to support the safety assessment of AAV-based gene therapies.